Targeting Of Ligand Binding Sites In ClfA
Abstract
The present invention provides methods and compositions to reduce binding of fibrinogen to the ClfA in a gram positive bacterial infections using monoclonal antibody, a polyclonal antibody, an antigen-binding antibody fragment or a composition that specifically binds to a portion of ClfA with the sequence of SEQ ID No: 15, SEQ ID NO: 16, SEQ ID NO: 17, and SEQ ID NO: 18.
Subject
A61K 31/65A61K 45/05
A61K 39/40
A61K 31/436
A61K 39/085
A61K 31/496
A61K 31/43
C12N 15/00
C07K 16/1271
A61K 31/4174
A61P31/04
C07K 2317/34
C07K 2317/92
C07K 2299/00
C07K 2317/24
Collections
Citation
Ganesh, Vannakambadi K.; Hook, Magnus (9/20). Targeting Of Ligand Binding Sites In ClfA. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /197563.